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R. Rodrigues

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Review Open access Oct 2026

Metabolic dysfunctions in pancreatic ductal adenocarcinoma: Pathogenic mechanisms and therapeutic implications.

Pancreatic ductal adenocarcinoma (PDAC) remains a highly aggressive malignancy characterized by a dismal prognosis and profound resistance to conventional therapies. Emerging evidence highlights systemic metabolic dysfunctions including obesity, dyslipidemia, type 2 diabetes mellitus (T2DM), and non-alcoholic fatty pan...

R. Rodrigues, Raquel Soares, M. H. Vasconcelos et al. · 0 citations

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