BACKGROUND
Schizophrenia is increasingly conceptualized as a disorder of circuit-level dysfunction. However, how thalamocortical abnormalities differ across cohorts with varying illness durations and relate to large-scale cortical hierarchical organization remains unclear.
METHODS
We analyzed resting-state functional...
Huan Huang, LENA PALANIYAPPAN, He-Chun Li et al.· Biological Psychiatry· 0 citations
Background Schizophrenia is characterized by substantial clinical heterogeneity, with average differences between males and females in symptom presentation, cognitive function, and treatment response. The cortico-thalamo-cerebellar circuit (CTCC) has been implicated in schizophrenia; however, whether schizophrenia-rela...
You-Xue Zhang, M. Duan, De-Zhong Yao et al.· Frontiers in Psychiatry· 0 citations
A distinctive subcortical FC pattern dominated by the striatum was identified that was associated with overall treatment outcomes in first-episode schizophrenia and was positively correlated with the actual reduction in PANSS total scores following antipsychotic treatment.
C. Hou, Huan Huang, Si-Si Jiang et al.· Schizophrenia Research· 0 citations
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