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Author

R. Roepman

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2 papers indexed here

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Open access Sep 2026

Primary cilia coordinate c-KIT signaling induced proliferation in alpha cells

Circulating glucagon levels are elevated in patients with diabetes and obesity and contribute to hyperglycemia. The mechanisms underlying hyperglucagonemia remain poorly understood, but expansion of pancreatic α-cell mass is thought to play an important role. Primary cilia are sensory organelles that act as signaling h...

Ganga Deshar, Mariam G. Aslanyan, Gaurav D. Diwan et al. · 0 citations
Review Open access Aug 2026

Understanding retinal regeneration: Core mechanisms and biological insights.

This review highlights current knowledge on the cellular and molecular basis of retinal regeneration and asks why regenerative capacity is maintained in some lineages but lost in others, and examines two principal cellular sources of retinal regeneration, which are the Müller glia and the retinal pigment epithelium.

Rens Hoekstra, Ivar Noordstra, Sakurako Kobayashi et al. · 0 citations

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