Author

R. Rofaeil

3 papers indexed here

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Review Aug 2026

Deciphering Gentamicin-Induced Nephrotoxicity and Hepatotoxicity: Pathophysiological Insights and Emerging Protective Approaches.

Gentamicin (GEN) is a critical aminoglycoside antibiotic for severe gram-negative infections, yet its clinical utility is limited by dose-dependent nephrotoxicity (occurring in 10-25% of therapeutic courses) and hepatotoxicity. Nephrotoxicity arises from GEN accumulation in proximal tubular cells, triggering reactive o...

Ehab E. Sharata, Reham H. Mohyeldin, Mahmoud Abdelnaser et al. · Food and Chemical Toxicology · 1 citation

Aug 2026

Neuroprotective Potential of Diacerein Against Cerebral Ischemia-Reperfusion Injury in Rats: Association with Modulation of Inflammatory and Hypoxia/Apoptosis-Related Signaling Markers

W. Abdelzaher, R. Rofaeil, Reham H. Mohyeldin et al. · SN Comprehensive Clinical Me... · 0 citations

Sep 2026

Imeglimin halts cyclophosphamide-induced ovarian injury: a dual modulation of TLR4/NF-κB/NLRP3-driven inflammation and AMPK/SIRT1/PGC-1α pathways.

Reham H. Mohyeldin, Ehab E. Sharata, Mahmoud Abdelnaser et al. · Naunyn-Schmiedeberg's Archiv... · 0 citations