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Open access Oct 2026

Salidroside inhibits glioma cell migration and proliferation through CYP2E1-neuroglobin-cytochrome c mediated redox axis

Glioblastoma (GB) represents one of the most aggressive primary brain tumors characterized by poor prognosis, high relapse and resistance to conventional therapies. Salidroside, a naturally occurring glucoside derived from Rhodiola rosea, has been reported to exhibit pro-apoptotic and anti-proliferative properties...

L. Panda, Kalpana K. Barhwal, Amit Kumar et al. · 0 citations
Open access Aug 2026

34 Therapeutic Targeting of the SLC7A11-GCLM-GPX4 Axis Sensitizes Glioblastoma to Ferroptosis and Associates with Poor Survival

The GPX-4/GCLM axis, which balances redox, is highly expressed and crucial for GBM cell survival and aggressive biological behavior and may be a valuable adjunct to diagnosis, as demonstrated by RSL3, FIN56, and BSO.

M. Behera, S. Purkait, Amit Ghosh et al. · 0 citations

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