Levodopa-related physiomarkers during deep brain stimulation in Parkinson’s disease
Adaptive deep brain stimulation (aDBS) can adjust stimulation to the (medication) state of patients with Parkinson’s disease using physiological biomarkers (physiomarkers), but whether individuals share a common physiomarker frequency remains unknown. We quantified levodopa-induced spectral changes (2–100 Hz) in loca...