Smart thermo/pH‑responsive Janus nanogel for synergistic chemo-magnetic hyperthermia therapy inducing caspase‑mediated apoptosis in the BALB/c 4T1 breast cancer model.
Effective treatment of aggressive breast tumors remains challenging due to poor drug selectivity, systemic toxicity, and limited therapeutic synergy. Here, a thermo/pH‑responsive magnetic Janus nanogel was employed as a smart platform for on‑demand co‑delivery of 5‑fluorouracil (5‑Fu) and quercetin (Qu) combined with m...