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Meta-analysis Open access Sep 2026

Duloxetine for postoperative pain management in total hip and knee arthroplasty: a systematic review and meta-analysis

Postoperative pain following total hip arthroplasty (THA) and total knee arthroplasty (TKA) drives opioid dependence. Perioperative duloxetine is an option as a multimodal analgesic adjunct, yet its efficacy and safety in this population are not fully defined. This systematic review and meta-analysis compared periopera...

Abdelrahman Ibrahim, Mohamed Abdelnabi, R. Sheta · 0 citations

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