Jul 2026
Abstract A033: Integrating cell-SELEX and deep learning method for discovery of high-affinity aptamers targeting cholangiocarcinoma
Cholangiocarcinoma (CCA) is an aggressive biliary malignancy with poor prognosis and limited treatment options, underscoring the need for targeted RNA-based therapeutic strategies. Though DNA- aptamers could be one of the promising targeted ligands, conventional enrichment-driven selection often fails to reliably ide...
Sourav Pal, Julia Driscoll, Brandon A. Wilbanks et al.
· Clinical Cancer Research · 0 citations