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R. Tewhey

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Sep 2026

Germline noncoding risk variants influence clonal hematopoiesis through altered hematopoietic enhancer activity.

Clonal hematopoiesis of indeterminate potential (CHIP) is a precursor condition characterized by the expansion of mutant hematopoietic stem and progenitor cell (HSPC) clones that increases the risk of hematologic malignancies. Although genome-wide association studies have identified multiple non-coding loci associated...

Trieu Nguyen, Jessica Jeejan, T. Iwasaki et al. · 0 citations
#artificial intelligence Preprint Aug 2026

Science sandboxes measure the scientific capability of AI agents

This work instantiates science sandboxes, a framework for studying this capability in AI agents through repeated cycles of experimentation, feedback, and hypothesis revision, in two biological settings, models of regulatory genomics and protein fitness prediction, and examines the capabilities of frontier agents.

Arya S. Rao, Rodrigo I. Castro, Sager J. Gosai et al. · 0 citations

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