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Author

R. Tőtős

2 papers indexed here

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Open access Oct 2026

Unconventional Yeasts as Whole-Cell Biocatalysts for Carboligase-Mediated Synthesis of Optically Active Acyloins

Background/Objectives: α-Hydroxy ketones (acyloins) are valuable chiral building blocks widely used in the synthesis of pharmaceuticals and fine chemicals. Their stereoselective synthesis remains challenging, driving interest in sustainable biocatalytic approaches for asymmetric C–C bond formation. Methods: Here, non-c...

M. Lăcătuș, R. Tőtős, M. Toșa et al. · 0 citations
Open access Sep 2026

Synthesis, molecular dynamics, and antimicrobial evaluation of peptide-antibiotic conjugates designed for dual-mechanism pathogen inhibition

These in vitro assays demonstrate retained peptide membrane-disrupting properties and synergistic effects with the antibiotics, and represents a promising strategy to reduce toxicity and overcome antimicrobial resistance.

Denisa Leonte, Clemence Fartaoui, Ioana Ionuț et al. · 0 citations

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