Stably, a Python package that implements stability selection with formal false positive control for DIA proteomics data, is developed and shows that the Shah and Samworth complementary pairs stability selection framework recovers more true synthetic biomarkers than the Meinshausen and Bühlmann framework at moderate eff...
Daniel Byrne, M. McNamara, R. Unwin· bioRxiv· 0 citations
The incidence of endometrial cancer is rising globally, placing significant burden on diagnostic pathways for women with abnormal uterine bleeding. Current evaluation relies primarily on transvaginal ultrasound followed by invasive endometrial visualisation and sampling, although most symptomatic women have no sinister...
Molly Dore, Jiexin Cao, Holly Baker-Rand et al.· British Journal of Cancer· 0 citations
This work illustrates an initial step toward improving protein quantification starting at the spectral library level by filtering precursors which are poor quantitative representatives of their parent proteins, which could enable development of universal tissue-specific refined spectral libraries able to improve quanti...
Bethany A. Barnes, Haneen Alharbi, R. Unwin· bioRxiv· 0 citations
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