Common variable immunodeficiency (CVID) is frequently complicated by autoimmune and inflammatory manifestations associated with profound immune dysregulation (CVIDc), including expansion of T-bethighCD21low B cells (CD21low B cells). Elevated serum IL-10 levels have repeatedly been reported in CVIDc, yet their relation...
Victoria Cousin, A. Graumann, V. Geiger et al.· Journal of Clinical Immunolo...· 0 citations
Personalis provides a proof-of-concept medical software for integrating heterogeneous clinical data with configurable ML-based prediction and interpretation workflows for autoimmune diseases, and offers a mechanistic overview of the parameters that mostly influence the prediction of the machine learning models, therefo...
Patrick Meier, Jan Kruta, Nicolas Bopp et al.· BMC Medical Informatics and...· 0 citations
AxSpA shows enrichment of innate-associated and broadly activated immune features, whereas PsA is characterized by adaptive and memory-associated immune responses, which may support biomarker-guided stratification within the SpA spectrum.
N. Frede, Nils Craig-Müller, Silke Kohrt et al.· Arthritis & Rheumatology· 0 citations
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