Author

R. Woods

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Open access Jul 2026

Conformational dynamics of exopolysaccharides underlie biofilm matrix mechanics in Vibrio cholerae

This paper systematically characterize various polymer properties of Vibrio polysaccharide (VPS), the major exopolysaccharide in biofilms formed by Vibrio cholerae, the causative agent of pandemic cholera.

Kee-Myoung Nam, Nathan Fowler, Rajan Kandel et al. · bioRxiv · 0 citations

Open access Aug 2026

Structure of a key adhesin-exopolysaccharide interaction provides insights into matrix assembly in Vibrio cholerae biofilms

The structure reveals for the first time the interaction between a biofilm exopolysaccharide and matrix protein, as well as insights into conformational changes of exopolysaccharide induced by this binding, and provides a generalizable approach for studying the biophysical and biochemical properties of carbohydrate-dep...

Alex Hinbest, Hyerim Bianca Nam, E. Liszczyk et al. · bioRxiv · 0 citations