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Author

R. Zenobi

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3 papers indexed here

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Sep 2026

Structural Mass Spectrometry Resolves the Conformational Dynamics of Semaglutide Oligomerization

Recent studies showed that several widely used glucagon-like peptide-1 receptor agonists (GLP-1RAs) can self-assemble into dynamic oligomeric species and ultimately less-regular, non-amyloid aggregates. While mature aggregates can be characterized by high-resolution microscopy methods, probing the conformational dyna...

Si-Ga Huang, Yu-Ye Zhou, Tin-yi Lui et al. · 0 citations
Sep 2026

Rapid Simultaneous Quantification of Four Typical Phthalate Esters in Complex Food Matrices via Thermal Desorption–Dielectric Barrier Discharge Ionization Mass Spectrometry

Conventional analytical methods for detecting and quantifying phthalate esters (PAEs) in foods generally require lengthy sample pretreatment procedures and suffer from severe matrix interferences. To address these shortcomings, a fast analytical platform based on a thermal desorption unit that is directly interfaced...

Qi-Sen Huang, Wei-Peng Cai, Xiao-Kang Guan et al. · 0 citations
Open access Aug 2026

Studying Mucin-Derived O‑Glycopeptides with Gas-Phase FRET

At least 50% of human proteins are glycosylated, however, it is not fully understood how glycosylation affects glycopeptide structures. For the highly O-glycosylated tandem repeats of the gel-forming mucin MUC5AC, it has been shown that glycoclustering leads to significant stiffening of the peptide backbone in solution...

Kim Greis, Arseniy Galashov, Lyna Bourehil et al. · 0 citations

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