Open access
Aug 2026
IGF2BP3-mediated regulation of the RNA isoform and modification landscape in pancreatic cancer.
The incidence of pancreatic ductal adenocarcinoma (PDAC) is increasing but clinical outcomes remain poor and new treatments are required. IGF2BP3 is an oncofetal m6A-reading RNA regulatory protein whose expression is commonly observed in PDAC and which may represent an important therapeutic target. IGF2BP3 protein is e...
Sandra Margielewska-Davies, W. Croft, Hayden Pearce et al.
· Oncogene · 0 citations