Granulomatous-lymphocytic interstitial lung disease (GLILD) develops in 10–30% of patients with common variable immunodeficiency (CVID) as a consequence of immune dysregulation. Therefore, immunoglobulin (Ig) M, produced by apoptosis-resistant plasmablasts in extrafollicular sites in the lungs, and serum soluble in...
Aleksandra Dašić, Rada Mišković, S. Janković et al.· Journal of Human Immunity· 0 citations
22q11.2 deletion syndrome (22q11.2 DS) is one of the most common microdeletion syndromes, characterized by congenital anomalies and variable immune dysfunction secondary to thymic hypoplasia. The resulting immune dysregulation frequently predisposes affected individuals to autoimmune manifestations, including immun...
Ana Drazic, S. Pasic, Maja Stojanović et al.· Journal of Human Immunity· 0 citations
Inborn errors of immunity (IEIs) frequently present with rheumatologic and autoimmune manifestations that closely mimic common polygenic conditions, including systemic lupus erythematosus, juvenile idiopathic arthritis, and vasculitis, posing significant challenges to early recognition and diagnosis. Current data indic...
Rada Mišković· Journal of Human Immunity· 0 citations
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