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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Rafael C. Bernardi

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Open access Aug 2026

Mapping of dynamic allostery within p38 alpha kinase via network analyses and NMR spectroscopy

Dynamical network analysis is used to identify key residues involved in a dynamic allostery between the N- and C-lobes that connects the major functional units of the MAP kinase p38α, providing mechanistic insight into p38α allostery and suggesting viable opportunities for the rational design of allosteric modulators of MAP kinases.

Suchandra Roy Acharyya, J. Weisner, Rafael C. Bernardi et al. · 0 citations

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