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Author

Rafael García-Martínez

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Open access Oct 2026

Iturin A disrupts Cryptococcus neoformans membrane integrity, attenuates virulence, and synergizes with amphotericin B

Cryptococcus neoformans is a major fungal pathogen with severely limited therapeutic options. We evaluated the antifungal activity of the lipopeptide iturin A against eight clinical isolates of C. neoformans. Iturin A exhibited robust anti-cryptococcal activity, with minimum inhibitory concentrations ranging from 12.5...

Yehia Elgammal, Rafael García-Martínez, C. Charles-Niño et al. · 0 citations

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