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Rafael R. Canevarolo

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Open access Jul 2026

Fluctuating environment causes neoplastic transition and epithelial-mesenchymal plasticity in human cells

The immortalized non-tumorigenic breast epithelial cell line (MCF10A) develops neoplastic clones under fluctuating conditions in-vitro that mimic the harsh tumor microenvironment and is identified as a potential therapeutic target against epithelial-mesenchymal plasticity and metastatic spread in breast cancer.

Erez Persi, Rafael R. Canevarolo, P. Sudalagunta et al. · 1 citation