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Author

Rafal Chojak

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2 papers indexed here

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Open access Sep 2026

Temozolomide-associated inflammatory-repair remodeling in recurrent glioblastoma exposes a ROCK-linked therapeutic vulnerability

Background Glioblastoma (GBM) adapts to therapy through coordinated malignant-cell and microenvironmental responses, but the mechanisms linking treatment-associated inflammation to tumor-cell phenotypic plasticity remain poorly defined. Here, we investigated whether preoperative temozolomide exposure is associated with...

Rafal Chojak, Umme H. Faisal, Priya U. Kumthekar et al. · 0 citations
Review Open access Aug 2026

The intersection of chemokine signaling with the hallmarks of cancer in glioblastoma

Glioblastoma, IDH-wildtype, is characterized by diffuse invasion, profound immunosuppression, treatment resistance, and near-inevitable recurrence. Although canonical genetic alterations establish malignant capacity, they do not fully explain how glioblastoma cells adapt to hypoxic, perivascular, invasive, immunosuppre...

Rafal Chojak, Jillyn Turunen, Noah B. Drewes et al. · 0 citations

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