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Author

Raghavendra Vadla

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2 papers indexed here

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Open access Sep 2026

SNP rs2853669 potentially elevates the risk of glioblastoma development and leads to worse prognosis when in cis with mutant TERT promoter in a Japanese cohort.

BACKGROUND Mutations in the telomerase reverse transcriptase (TERT) promoter region (TPM), particularly C228T and C250T, are common in IDH-wildtype glioblastoma (GBM). The single nucleotide polymorphism (SNP) rs2853669, also located in the TERT promoter, may influence telomerase activity, though its clinical relevance...

Daisuke Kawauchi, Yohei Miyake, B. Taylor et al. · 0 citations
Jul 2026

Reprogramming of Glioblastoma-Immune Crosstalk to Overcome Immunotherapy Failure 2258791

A targetable molecular axis linking the bromodomain-containing protein 2 (BRD2) complex to fibronectin-driven immune suppression in mesenchymal-like GBM niches is identified, offering a promising combinatorial therapeutic strategy.

Shuozhi Liu, Lizmarie Garcia-Rivera, Michael A. LaPorta et al. · 0 citations

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