Open access
Jul 2026
Integrative bioinformatics analysis identifies APOE as a candidate link between lipid dysregulation and macrophage activation in inborn errors of metabolism
The hypothesis that APOE-associated lipid dysregulation may contribute to macrophage dysfunction and warrant further experimental validation is supported and identified as a highly prioritized candidate gene associated with lipid metabolism pathways and macrophage-related signatures in IEM.
Rahmat Dani Satria, Riswan Hadi Kusuma, Nazhipah Isnani et al.
· Frontiers in Pharmacology · 0 citations