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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Raj Kumar

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2 papers indexed here

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Open access Aug 2026

Structural and mechanistic analysis of semisynthetic α-mangostin derivatives with anticancer activity via topoisomerase II inhibition.

Eleven novel alkyl/arylalkyl substituted α-mangostin derivatives (M2-M12) were synthesized from isolated α-mangostin (M1) from the pericarp of Garcinia mangostana L. extract. Among all the compounds, M10 exhibited the most potent antiproliferative activity against MCF-7 cells, with an IC₅₀ of 8.39 ± 0.07 μM, comparable...

M. K. Katiyar, Faheem Ahmed, Sonali Priyadarshini et al. · 0 citations
Review Sep 2026

Drug discovery strategies targeting B7-H3 (CD276) in lung and gastric cancers: From biological validation to next-generation small molecules, biologics and cell-based immunotherapies.

B7 homolog 3 protein (B7-H3, also known as CD276) has emerged as a promising immune checkpoint target because of its high expression in solid tumors, limited presence in normal tissues and roles in immune evasion and tumor progression. This review focuses on the biological and therapeutic relevance of B7-H3 in lung and...

Soorya Suresh, Surabhi Maurya, Kajal Singh et al. · 0 citations

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