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Author

Raj Kumar Kodishala

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Open access Sep 2026

Eco‐Friendly LC–MS/MS Determination of N ‐Nitroso Vildagliptin Amide, a Nitrosamine Carcinogenic Impurity, in Vildagliptin Drug Substance Using Advanced Greenness Metrics

In the process of making vildagliptin (VG) API, one of the nitrosamine groups found in the drug is N ‐nitroso vildagliptin amide (NVA). This led to the development of a multi‐reaction monitoring (MRM) approach that is both sensitive and reliable for quantitatively assessing NVA impurity in VG API. Using isocratic...

Raj Kumar Kodishala, Kousrali Sayyad, Pravardhan Reddy Elala et al. · 0 citations

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