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Rajat Gupta

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Open access Sep 2026

Air Pollution Triggers Metabolomic Signature of Mitochondrial Dysfunction in Mice and Humans: Implications for Cardiovascular Disease Development

Background: Previous animal studies found that subchronic exposure to diesel exhaust (DE) induces hyperlipidemia, accompanied by upregulation of 12- and 15-lipoxygenase (LOX) pathways and hepatic mitochondrial dysfunction. However, the human relevance of these findings has not been established. Methods: We studied ApoE...

Yan Lin, Xing-Hua Qiu, Rajat Gupta et al. · 0 citations

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