Open access
Oct 2026
A voltage-gated porin PPE1 regulates secretion and drug resistance in Mycobacterium tuberculosis.
Drug resistance in Mycobacterium tuberculosis (Mtb) remains a formidable clinical hurdle, compounded by the fact that the pathways by which antibiotics penetrate its multilayered cell envelope remain incompletely mapped. We identify PPE1 as a voltage-gated outer-membrane porin that mediates the secretion of kupyaphores...
Mohit Yadav, Neilah Firzan C. A, D. Mandal et al.
· Proceedings of the National... · 0 citations