Open access
Jul 2026
Free energy spectroscopy reveals the mechanistic landscape of chromatin compaction
Abstract Eukaryotic genomic DNA is repeatedly wrapped into nucleosome spools: the basic building block of chromatin. This organization regulates the physical accessibility of the genome to gene transcription, replication, and repair regulatory factors. Chromatin compaction is controlled by multivalent weak interactions...
Kalven Bonin, Yuchen Wang, Ivan Riveros et al.
· Nucleic Acids Research · 0 citations