Author

Ramanathan Karuppasamy

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Open access Sep 2026

Template‐Derived Engineering of Peptide Inhibitors Targeting HSP90–CDC37 Interface: A Theoretical Framework for Cancer Therapeutics

Findings identify Pep14 derived from Template‐2 as a lead peptide candidate for disrupting the HSP90–CDC37 interaction, however, further experimental validation is required to confirm its therapeutic potential in cancer treatment.

Sarath Perumal, Ramanathan Karuppasamy · ChemistrySelect · 0 citations

Open access Aug 2026

Design and development of novel peptidomimetic compounds for cancer therapeutics: Focus on HSP90–CDC37 interaction

This study highlights MMs02350546 as a potential disruptor of HSP90–CDC37 interaction, presenting a promising therapeutic strategy against cancer via chaperone complex destabilization.

Sarath Perumal, Ramanathan Karuppasamy · BioMedicine · 0 citations

Open access Jul 2026

Comparative transcriptomic analysis identifies conserved abiotic stress-responsive hub genes in Sorghum bicolor.

The identified genes provide a foundation for future experimental validation and functional studies aimed at developing climate-resilient sorghum cultivars and highlight potential genetic targets for improving stress tolerance in sorghum.

Renuka Suresh, Ramanathan Karuppasamy · BMC Plant Biology · 0 citations