ABSTRACT Reporter-expressing recombinant influenza A viruses (IAVs) have emerged as powerful tools for studying viral infection, host–pathogen interactions, and the identification and characterization of prophylactic and/or therapeutic countermeasures for the treatment of IAV infections. By incorporating a reporter gen...
Ramya S. Barre, H. Nath, A. Nogales et al.· Journal of Virology· 0 citations
The development and implementation of this multivalent LAIV as a broadly protective pan-H5N1 LAIV for pandemic preparedness are supported and the feasibility of developing and implementing this multivalent LAIV as a broad protective pan-H5N1 LAIV against divergent H5N1 viruses for human use is demonstrated.
Ahmed M. Elsayed, Ramya S. Barre, Arash Rahmani et al.· bioRxiv· 0 citations
The results demonstrate the feasibility of using rBA.5 ZsG-Nluc to track viral infections and identify prophylactics and therapeutics against recent SARS-CoV-2 VoCs in vitro, ex vivo, and in vivo.
Esteban M. Castro, Ramya S. Barre, C. Ye et al.· bioRxiv· 0 citations
Using the ferret model of influenza infection and transmission, it is demonstrated that the currently circulating B3.3.13 is already well adapted for mammalian infection and transmission whereas D1.1 rapidly acquires mammalian-adaptive mutations after a single infection and/or transmission event, highlighting its evolu...
Ahmed M. Elsayed, Ramya S. Barre, Mahmoud Bayoumi et al.· bioRxiv· 0 citations
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