Ramzi Maadadi

Organic synthesis and antiarthritic effect of 3-hydroxy-1,7-bis (3-nitrophenyl)hepta-1,3,6-trien-5-one against formaldehyde-induced arthritis in mice.

Design and synthesis of novel 4-substituted 1,4-dihydropyridine (DHP) derivatives, molecular docking and anti-oxidant activity

Abstract A new series of 1,4-dihydropyridine derivatives bearing a benzoic acid at the N-position were prepared by Hantzsch syntheses with piperidine as the catalyst, enamine of dimedone and 2-benzylidenemalononitrile as starting materials. Various substituted substrates were successfully used, affording the N-substitu...

Crystal structure, intermolecular interactions, Hirshfeld surface analysis, theoretical studies and biological evaluation of (E)-5-(benzyloxy)-2-{[(2,5-dimethoxyphenyl)imino]methyl}phenol, a new Schiff base.

Results indicate an enzyme-dependent inhibitory profile rather than uniformly superior activity relative to the reference inhibitors, and quantum theory of atoms in molecules (QTAIM) analysis was performed to characterize selected intra- and intermolecular interactions.