P2P: Cross-View Population Denoising for Unpaired Single-Cell Perturbation Response Prediction
AIVC (AI Virtual Cell) is a learned simulator of cellular behavior across conditions. Predicting how a cell population responds transcriptionally to a genetic perturbation is a core task. Perturb-seq records that response by destructive sequencing, so a control cell and a perturbed cell are never observed as a pair, an...
Hao-Jie Yang, Ran Su
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