Open access
Sep 2026
A QUALITY BY DESIGN APPROACH FOR THE DEVELOPMENT AND VALIDATION OF A REVERSE-PHASE ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS ESTIMATION OF ACEBROPHYLLINE AND N–ACETYLCYSTEINE IN BULK AND PHARMACEUTICAL DOSAGE FORM
Objectives: The aim of this study was to develop and validate an accurate, fast, and reliable stability-indicating reverse-phase ultra-performance liquid chromatography (RP–UPLC) technique based on quality by design (QbD) for acebrophylline (ACB) and N–acetylcysteine (NAC) simultaneously in pure and tablet formulation....
Jerom Md, Ranganath Mk, Chaithanya Sudha Pd
· Asian Journal of Pharmaceuti... · 0 citations