Open access
Jul 2026
Mechanistic evaluation of NSC 57774 as a SHP2 inhibitor in gastric cancer: Multi-pathway signaling modulation in vitro
Findings position NSC 57774 as a promising candidate for targeted gastric cancer therapy, capable of disrupting multiple signaling pathways involved in tumor progression, metastasis, and inflammation, warranting further preclinical and clinical investigation.
Ghalia Khoder, Rose Ghemrawi, Nour Sammani et al.
· PLoS ONE · 0 citations