Open access
Aug 2026
Comparative analysis of microglia-targeted AAVs reveals capsid choice drives efficiency in vitro but has limited impact in vivo
Improved capsids for in vitro manipulation of microglia are developed and viral genome design, not capsid identity, is established as the principal determinant of efficient in vivo microglial targeting.
Saša Jereb, Lia R. D’Alessandro, Nader Morshed et al.
· bioRxiv · 0 citations