Author

Rasha Alonaizan

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Oct 2026

Integrating in vitro and in silico correlation of thiazole-based carboxamide derivatives as promising SARS-CoV-2 papain-like protease inhibitors: a versatile approach for COVID-19 therapy

Abstract A new series of thiazole-based carboxamide derivatives (5–12) was designed, synthesized with structural elucidation performed using standard spectroscopic techniques including NMR and HRMS. The synthesized compounds were evaluated for their inhibitory activity against SARS-CoV-2 papain-like protease (PLpro) an...

Imran Khan, Rafaqat Hussain, Hina Sarfraz et al. · Zeitschrift für Naturforschu... · 0 citations

Open access Sep 2026

Integrated Biomarker Assessment of Bifenthrin, Chlorpyrifos and Endosulfan Toxicity in Indigenous Carps (Catla catla and Labeo rohita): Oxidative Stress, Genotoxicity and Nuclear Alterations

ABSTRACT Background The extensive use of pesticides in agriculture has increased their runoff into aquatic ecosystems, posing serious risks to non‐target organisms. Fish are recognized as sensitive bioindicators and are widely used to evaluate the ecological impacts of pesticide contamination. Objective This study inve...

H. Naz, S. Abdullah, T. Ahmed et al. · Veterinary Medicine and Scie... · 0 citations

Open access Aug 2026

Structure-Guided Immunoinformatics for the Rational Design of a Multi-Epitope Vaccine Against Batai Orthobunyavirus

This study presents a structurally optimized and validated multiepitope vaccine candidate against the emerging Batai orthobunyavirus, identifying a promising vaccine candidate for further investigation; however, its immunogenicity, safety, and protective efficacy before further vaccine development can be considered.

M. A. Alwaili, N. Al‐Hoshani, Huda A Alqahtani et al. · Pharmaceuticals · 0 citations