Robust Transcription Factor Binding Site Prediction and Explainability Using a Heterogeneous Mixture of Experts Architecture
Transcription Factor Binding Site (TFBS) prediction is central to understanding gene regulation and various biological processes. This study introduces HetMoE, a heterogeneous, embedding-gated Mixture-of-Experts for TFBS prediction. A gating network operates on the embeddings produced by a pool of complementary expert...