Siderophore-Enabled Delivery of Carbapenem and Metallo-β-Lactamase Inhibitor: A Promising Strategy against Multidrug-Resistant Pseudomonas aeruginosa
Carbapenem-resistant Pseudomonas aeruginosa (CRPA), a World Health Organization high-priority pathogen, represents a major clinical threat due to limited treatment options. Its intrinsic resistance is driven in part by extremely low outer-membrane permeability, which restricts antibiotic uptake, while the increasing...