Regenerative therapies for knee osteoarthritis: a systematic review and meta-analysis of platelet-rich plasma and mesenchymal stromal cells with narrative synthesis of extracellular vesicles
Osteoarthritis (OA) is a leading cause of pain and disability worldwide, with current treatments primarily focused on symptom relief rather than disease modification. In recent years, regenerative therapies such as platelet-rich plasma (PRP), mesenchymal stem cells (MSCs), and extracellular vesicles (EVs) have gain...