Open access
Jul 2026
SOCS3 deficiency drives the primed to naive pluripotency transition by sustaining STAT3 activation
Eliminating SOCS3-mediated negative regulation to sustain STAT3 activation is an effective strategy to overcome stem cell reprogramming barriers, providing a key target for the precise manipulation of pluripotent stem cell (PSC) fate.
Ren-Hong Lu, Suoni Huang, Mingyang Du et al.
· Frontiers in Genetics · 0 citations