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Renata K. Carvalho

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Review Oct 2026

What can narcolepsy teach us about hypocretin and dementia?

Sleep and circadian disturbances are associated with cognitive decline and dementia. Narcolepsy type 1 (NT1), characterized by severe sleep-wake disruption and loss of hypocretin, would therefore be expected to predispose individuals to premature brain aging. Yet available biomarker and neuroimaging findings do not con...

Renata K. Carvalho, T. Alvarenga, F. Coelho et al. · 0 citations

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