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Reoto Moroi

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Open access Sep 2026

DNA polymerase I is required for the Hachiman-family anti-phage defense system

ABSTRACT Abortive infection (Abi) systems protect bacterial populations from bacteriophages by triggering growth arrest or cell death in infected cells; however, how Abi effectors are coupled to changes in host DNA replication and repair remains unclear. The widely conserved Hachiman defense system encodes a nuclease (...

Saya Takita, Reoto Moroi, Haruka Terasaki et al. · 0 citations

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