Structural insights into γ-presodorifen pyrophosphate synthase.
Canonical terpenoids conform to the (C5H8)n formula, whereas an emerging group of terpenoids that break the isoprene rule have been discovered recently. The precursor of C17 homosesquiterpenoid chlororaphens is derived from converting canonical C15 farnesyl pyrophosphate (FPP) by two consecutive methyltransferases (MTs...