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Author

Rezwanul Islam

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Jul 2026

SHMT2 Regulates T Cell Homeostasis and Mucosal Inflammation Via Metabolic and Lipid Remodeling 2256280

The loss of SHMT2 in T cells disrupted mitochondrial one-carbon metabolism, induced redox imbalance and enhanced neutral lipid storage and phospholipid synthesis, with compensatory arginine-proline upregulation and taurine depletion to sustain survival under oxidative stress.

Lamis El-Baz, Michael C. McGee, Rezwanul Islam et al. · 0 citations

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