Ricardo A Matute

Hydrophobicity and signal sequence binding to the Sec complex: A single molecule biophysical perspective.

The Sec61 complex plays a critical role in protein translocation into the endoplasmic reticulum (ER), enabling the passage of soluble proteins into the lumen and the lateral insertion of membrane proteins. The Sec complex, comprising Sec61, Sec63, Sec62, and other auxiliary proteins, is especially important for the tra...