Author

Riccardo De Santis

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Open access Aug 2026

Exploring the Pyrimidine Scaffold for the Development of SARS-CoV-2 Mpro Inhibitors.

New SARS-CoV-2 Mpro small-molecule inhibitors endowed with a pyrimidine scaffold are designed and synthesized and the mechanism of action of the most promising compound was elucidated.

Salvatore Nieddu, Giuseppe Ruggieri, Riccardo De Santis et al. · ACS Infectious Diseases · 0 citations