Author

Richard J. Payne

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Review Sep 2026

Precision Protein Modification via Ligation and Bioconjugation at Selenocysteine.

These technologies represent a major advance in the generation of site-selectively modified peptide and protein diselenides and proteins, unlocking new possibilities for applications in fundamental biology but also the generation of next-generation diagnostics and therapeutics bearing precise modifications at defined s...

Max J. Bedding, Sameer S. Kulkarni, Richard J. Payne · Accounts of Chemical Researc... · 0 citations

Open access Aug 2026

Development of macrocyclic peptide inhibitors of Mycobacterium tuberculosis MurF via mRNA display with genetic reprogramming.

The development of new antibacterials for Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains critical due to the continued global burden of disease and the emergence of multi-drug resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains. The MurF enzyme, which catalyses the AT...

Patrick W. Carlos, Charlotte Franck, Caitlin E. Clarke-Shepperson et al. · RSC Medicinal Chemistry · 0 citations