Open access
Sep 2026
Antimicrobial peptide Pt5-1c exerts potent immunomodulatory and antiviral effects by facilitating cellular delivery of cGAMP
The cGAS-STING signaling axis constitutes a pivotal defense mechanism in innate immunity, where the second messenger cyclic 2’, 3’-GMP-AMP (hereafter referred to as cGAMP) orchestrates the induction of type I interferons (IFNs) to combat viral infections. Despite its therapeutic potential, the clinical translation of c...
Xue-Lian Zhao, Ze-Tao Ding, Jing-Wei Zhang et al.
· Frontiers in Immunology · 0 citations