Open access
Aug 2026
Matrix stress relaxation drives glioblastoma cell response in viscoelastic biomaterials
The extracellular matrix (ECM) of glioblastoma (GBM) is known to modulate cell behavior, yet the specific contributions of matrix biochemical and biomechanical signaling remain poorly understood. To address this, we engineer a tunable hyaluronan-elastin-like protein (HELP) hydrogel to independently control ligand prese...
S. Ghorbani, Michelle S. Huang, Dai-Yao Zhang et al.
· Science Advances · 0 citations