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Risako Tamura

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Open access Sep 2026

Loss of Newborn Neuron Function Promotes Aβ Accumulation in an Alzheimer's Disease Mouse Model.

Whether the loss of adult hippocampal newborn neuron (NBN) function contributes to Alzheimer's disease (AD) amyloid pathology remains unclear. Adult NBNs regulate dentate gyrus (DG) circuitry, and their decline has been observed during AD progression. To investigate their role, we generated NBN-APP mice by crossing APP...

Risako Tamura, Riki Kawabata, Chen-Xu Lei et al. · 0 citations

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